In the 1960's some scientists made an exact replica of a brain, and still haven't got any thought out of it. We know that we are an intelligence. Yet when people lose a bit of brain they can have difficulty doing things. Two people can lose the same bit of brain matter and one may walk again and the other not. Also one girl was born with absolutely no brain whatsoever and yet lived for 27 days. An autopsy revealed only a liquid where the brain should be.
I saw a special on all these people in Europe who were born with less than normal brain (many not even having the so-called "human section" which is supposed to be why we are superior to apes). Yet all these people were perfectly normal.
However if someone suddenly loses a part or a part is suppressed by medicine then problems occur. This leads me to feel that our intelligence has to respond to changes where the brain suffers problems. And this is obviously a large challenge.